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Anti-PHGDH/Malate dehydrogenase Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PHGDH rabbit polyclonal antibody |
Gene Name: | D-3-phosphoglycerate dehydrogenase |
Synonyms: | 3-PGDH, A10, Phgdh, 3-phosphoglycerate dehydrogenase |
Immunogen: | Recombinant protein corresponding to Mouse PHGDH |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 57 kDa |
Uniprot ID: | O43175, Q61753, O08651 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, lymph node |
Background
PHGDH gene encodes the D-3-phosphoglycerate dehydrogenase which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms.
Images
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Western blot analysis of Phgdh (GB111117) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
