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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PIKE rabbit polyclonal antibody |
Gene Name: | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 |
Synonyms: | AGAP-2, Agap2, ANK repeat and PH domains 2, Arf GAP with GTP binding protein like, Centaurin gamma 1, Centg1, Cnt-g1, GGAP2, Nuclear GTPase PIKE, PI3K ENHANCER, PIKE |
Immunogen: | Recombinant protein corresponding to Mouse PIKE |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 125 kDa |
Observed MW. | 125 kDa |
Uniprot ID: | Q3UHD9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | lung, heart |
Background
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. Aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase.
Images
 | Western blot analysis of AGAP2 (GB113941) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
