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Anti-PLCG 2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PLCG 2 rabbit polyclonal antibody |
Gene Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 |
Synonyms: | Plcg2, PLCG2, APLAID, FCAS3, PLC-IV, PLC-gamma-2, Phospholipase C gamma 2 |
Immunogen: | Recombinant protein corresponding to Mouse PLCG 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane, Cytoplasm |
Uniprot ID: | Q8CIH5, P24135 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 2000-1: 8000 | colon, skin, small intestine, spleen, stomach |
Background
Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C-beta is regulated by heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1) and C-gamma-2 (PLCG2) enzymes are controlled by receptor tyrosine kinases.
Images
 | Immunohistochemistry of paraffin embedded mouse skin using pclr2 (GB11733) at dilution of 1:2500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat small intestine using pclr2 (GB11733) at dilution of 1:2500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat stomach using pclr2 (GB11733) at dilution of 1:2500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse small intestine using pclr2 (GB11733) at dilution of 1:4000 (400x lens) |
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Immunofluorescence of paraffin embedded rat colon using pclr2 (GB11733) at dilution of 1:4000 (400x lens) |
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Immunofluorescence of paraffin embedded rat spleen using pclr2 (GB11733) at dilution of 1:4000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
