Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PLD1 rabbit polyclonal antibody |
Gene Name: | Phospholipase D1 |
Synonyms: | Pld1, PLD1, phospholipase D1, CVDD |
Immunogen: | Recombinant protein corresponding to Mouse PLD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | brain, breast cancer, spleen, testis |
Background
Phospholipase D1 is an enzyme encoded by the PLD1 gene. Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.
Images
Immunohistochemistry of paraffin embedded mouse brain using p1d1 (GB11903) at dilution of 1:2000 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse spleen using p1d1 (GB11903) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat brain using p1d1 (GB11903) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat testis using p1d1 (GB11903) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded human breast cancer using p1d1 (GB11903) at dilution of 1:500 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using p1d1 (GB11903) at dilution of 1:500 (400x lens) |
|
Immunofluorescence of paraffin embedded rat spleen using p1d1 (GB11903) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |