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Anti-PPAR gamma Mouse mAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Peroxisome proliferator-activated receptor gamma |
Synonyms: | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma, peroxisome |
Immunogen: | Recombinant protein corresponding to Mouse PPARγ |
Uniprot ID: | |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | adipose tissue |
Background
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.
Images
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Immunohistochemistry of paraffin embedded mouse fat using PPARγ (GB12164) at dilution of 1: 2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat fat using PPARγ (GB12164) at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
