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Anti-PPP2R1B Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PPP2R1B rabbit polyclonal antibody |
Gene Name: | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform |
Synonyms: | PP2A subunit A isoform PR65-beta, PP2A subunit A isoform R1-beta, Ppp2r1b, PPP4R1, PR65B |
Immunogen: | Recombinant protein corresponding to Mouse PPP2R1B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 66 kDa |
Observed MW. | 65 kDa |
Uniprot ID: | P30154, Q7TNP2, Q4QQT4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen |
Background
PPP2R1B is a member of the PP2A family. The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C.
Images
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Western blot analysis of PPP2R1B (GB111575) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
