Your shopping cart is empty!
Anti-PRMT5 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PRMT5 rabbit polyclonal antibody |
Gene Name: | Protein arginine N-methyltransferase 5 |
Synonyms: | PRMT5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog, SKB1 homolog, SKB1Hs, HRMT1L5, IBP72, JBP1, SKB1, PRMT5 |
Immunogen: | Recombinant protein corresponding to Human PRMT5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 73 kDa |
Observed MW. | 73 kDa |
Uniprot ID: | Q8CIG8 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 1000-1: 2000 | kidney |
Background
PRMT5 is a Type II enzyme that catalyzes arginine monomethylation and symmetric dimethylation (Rme1 and Rme2s). The many targets of PRMT5 include ribosomal proteins, the histone chaperone nucleoplasmin, p53, and histones. PRMT5 is frequently observed in a complex with the cofactor, methylosome protein 50 (MEP50), which is required for PRMT5 activity. PRMT5 is upregulated in several human malignancies, including lymphomas, lung cancer, breast cancer and colorectal cancer.
Images
 | Western blot analysis of Prmt5 (GB112970) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
