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Anti-Peroxiredoxin 2/PRP Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Peroxiredoxin 2/PRP rabbit polyclonal antibody |
Gene Name: | Peroxiredoxin-2 |
Synonyms: | Thiol-specific antioxidant protein, TSA, Thioredoxin peroxidase 1, Prdx2, Tdpx1, TpxThioredoxin-dependent peroxide reductase 1, Thioredoxin-dependent peroxiredoxin 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Peroxiredoxin 2/PRP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Uniprot ID: | P32119, Q61171, P35704 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, brain, kidney |
Background
PRDX2, also named as TSA, PRP, NKEFB and TDPX1, belongs to the ahpC/TSA family. It is known to act as an antioxidant enzyme whose main function is H2O2 reduction in cells. PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. It may play an important role in eliminating peroxides generated during metabolism. PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. PRDX2 actions may be related to the expression of NFKB and IKB.
Images
| Western blot analysis of Peroxiredoxin2 (GB111931) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
