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Anti-PSME1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PSME1 rabbit polyclonal antibody |
Gene Name: | Proteasome activator complex subunit 1 |
Synonyms: | IFI5111, IGUP I 5111, PA28A, PA28alpha, PSME1, REG alpha, REGalpha |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PSME1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 29 kDa |
Observed MW. | 34 kDa |
Uniprot ID: | P97371 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | lung |
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Images
 | Western blot analysis of PSME1 (GB113904) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
