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Anti-Phospho-mTOR (S2481) Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Serine/threonine-protein kinase mTOR |
Synonyms: | FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR, P-MTOR |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human mTOR (S2481) |
Uniprot ID: | P42345 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 289 kDa / 289 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | 293, NIH3T3, C6 |
Background
MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. MTOR has a calculated molecular mass of 289 kDa, and always can be detected at about 250 kDa due to some modifications.
Images
| Western blot analysis of P-mTOR (GB114489) at dilution of 1: 1000 Lane1: 293 untreated Lane2: 293 was starved overnight and then treated with 100nM insulin for 30min Lane3: NIH3T3 untreated Lane4: NIH3T3 was starved overnight and then treated with 100nM insulin for 30min Lane5: C6 untreated Lane6: C6 was starved overnight and then treated with 100nM insulin for 30min |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
