Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RAB11FIP3 rabbit polyclonal |
Gene Name: | Rab11 family-interacting protein 3 |
Synonyms: | ARFO1, Arfophilin 1, Eferin, FIP3 Rab11, KIAA0665, MU MB 17.148, Rab11 FIP3, RAB11FIP3 |
Immunogen: | Recombinant protein corresponding to Mouse RAB11FIP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 119 kDa |
Observed MW. | 90 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 800-1: 1500 | lung, prostate, kidney |
Background
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin.
Images
Western blot analysis of RAB11FIP3 (GB113223) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |