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Anti-RAB27A Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RAB27A rabbit polyclonal antibody |
Gene Name: | Ras-related protein Rab-27A |
Synonyms: | Rab27a, Rab27, Ras-related protein Rab-27A, Ras-related protein Rab27A |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RAB27A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 25 kDa |
Observed MW. | 28 kDa |
Uniprot ID: | Q9ERI2, P23640 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, ovary, kidney |
Background
Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.
Images
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Western blot analysis of RAB27A (GB111106) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
