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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RAC3 rabbit polyclonal antibody |
Gene Name: | Ras-related C3 botulinum toxin substrate 3 |
Synonyms: | Rac3, p21 Rac3, Rac1B, RAS related C3 botulinum substrate 3, Ras-related C3 botulinum toxin substrate 3, Rho family small GTP binding protein Rac3 |
Immunogen: | Recombinant protein corresponding to Mouse RAC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cell membrane |
Uniprot ID: | O09000 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 4000 | brain, pancreas |
Background
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Images
 | Immunohistochemistry of paraffin embedded mouse brain using Rac3 (GB11776) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using Rac3 (GB11776) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using Rac3 (GB11776) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat pancreas using Rac3 (GB11776) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
