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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | GTPase HRas/GTPase KRas/GTPase NRas |
Synonyms: | GTPase HRas, HRAS, C BAS/HAS, CTLO, HAMSV, KRAS, p21ras, NRAS, RASK2, N-RAS |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human KRAS+NRAS+HRAS. |
Uniprot ID: | P01116, P01111, P01112 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 21 kDa / 21 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain |
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
Images
| Western blot analysis of RAS (GB115457) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
