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Anti-RB associated KRAB repressor Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RB associated KRAB repressor rabbit polyclonal antibody |
Gene Name: | RB-associated KRAB zinc finger protein |
Synonyms: | RB-associated KRAB repressor, Zinc finger protein 769, Rbak, Znf769 |
Immunogen: | Recombinant protein corresponding to Mouse RB associated KRAB repressor |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8BQC8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 4000 | brain, heart, kidney, liver, lung, testis |
Background
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.
Images
| Immunohistochemistry of paraffin embedded mouse brain using RBAK (GB112588) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse heart using RBAK (GB112588) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using RBAK (GB112588) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using RBAK (GB112588) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded mouse liver using RBAK (GB112588) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded mouse lung using RBAK (GB112588) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded rat kidney using RBAK (GB112588) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded rat liver using RBAK (GB112588) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded rat testis using RBAK (GB112588) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
