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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RRP4 rabbit polyclonal antibody |
Gene Name: | Exosome complex component RRP4 |
Synonyms: | EXOSC2, exosome component 2, hRrp4p, p7, RRP4, Rrp4p |
Immunogen: | Recombinant protein corresponding to Mouse RRP4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 35 kDa |
Uniprot ID: | Q8VBV3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1500 | small intestine, liver |
Background
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.
Images
| Western blot analysis of EXOSC2 (GB114106) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
