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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Retinoschisin |
Synonyms: | Retinoschisin, retinoschisin 1, RS, RS1, XLRS1 |
Immunogen: | Recombinant protein corresponding to Mouse RS1 |
Uniprot ID: | Q9Z1L4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cell membrane. |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | eyeball |
Background
Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides (PubMed:17325137, PubMed:20677810). May play a role in cell-cell adhesion processes in the retina, via homomeric interaction between octamers present on the surface of two neighboring cells (By similarity). Required for normal structure and function of the retina (PubMed:11983912, PubMed:17325137). {ECO:0000250|UniProtKB:O15537, ECO:0000269|PubMed:11983912, ECO:0000269|PubMed:17325137, ECO:0000269|PubMed:20677810}.
Images
| Immunohistochemistry analysis of paraffin embedded mouse eyeball using RS1 (GB114495) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin embedded rat eyeball using RS1 (GB114495) at dilution of 1: 700 |
| Immunofluorescence analysis of paraffin embedded mouse eyeball using RS1 (GB114495) at dilution of 1: 700 |
| Immunofluorescence analysis of paraffin embedded rat eyeball using RS1 (GB114495) at dilution of 1: 700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
