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Anti-Rab11A Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Rab11A rabbit polyclonal antibody |
Gene Name: | Ras-related protein Rab-11A |
Synonyms: | Rab-11, Rab11a, Rab11 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Rab11A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | P62491, P62492, P62494 |
Images
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, spleen |
Background
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras super family of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane.
Images
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Western blot analysis of RAB11A (GB111127) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
