Your shopping cart is empty!
Anti-Rab17 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Ras-related protein Rab-17 |
Synonyms: | RAB17, Ras related protein Rab 17 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Rab17 |
Uniprot ID: | P35292 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 24 kDa / 26 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | liver |
Background
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface.
Images
| Western blot analysis of RAB17 (GB114756) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
