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Anti-Rad21 Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Double-strand-break repair protein rad21 homolog |
Synonyms: | hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog, 64-kDa carboxy-terminal product, Rad21, HR21, KIAA0078, NXP1, SCC1 |
Immunogen: | Recombinant protein corresponding to Mouse Rad21 |
Uniprot ID: | Q61550 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 72 kDa / 75 kDa/130 kDa |
Images
WB | Human | 1: 500-1: 1000 | HeLa, THP-1, K562 |
ICC/IF | Human | 1: 100-1: 400 | Hela |
Background
RAD21, also named as Nuclear matrix protein 1, which belongs to the rad21 family. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Images
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Western blot analysis of RAD21 (GB111435) at dilution of 1: 500 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using Rad21(GB111435) at dilution of 1: 100-1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
