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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Rad9 rabbit polyclonal |
Gene Name: | Cell cycle checkpoint control protein RAD9A |
Synonyms: | hRAD9, RAD9, RAD9 homolog A (S. pombe), RAD9A, DNA repair exonuclease rad9 homolog A, Rad9-like protein |
Immunogen: | Recombinant protein corresponding to Mouse Rad9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 42 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 800-1: 1500 | lung, testis |
Background
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.
Images
 | Western blot analysis of Rad9 (GB113416) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
