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| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | GTPase HRas/GTPase KRas/GTPase NRas |
Synonyms: | KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B,K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2, K-ras, KRAS proto-oncogene, GTPase, c-Ki-ras2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KRAS+NRAS+HRAS. |
Uniprot ID: | P32883,P08556,Q61411 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 21 kDa / 21 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1000 | lung, colon, kidney |
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
Images
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Western blot analysis of Ras (GB11411) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
