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Anti-RbAp48 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RbAp48 rabbit polyclonal |
Gene Name: | Histone-binding protein RBBP4 |
Synonyms: | CAF-1 subunit C, CAF-I 48 kDa subunit, CAF-I p48, Retinoblastoma-binding protein p48, Chromatin assembly factor 1 subunit C, Retinoblastoma-binding protein 4, Rbap48 |
Immunogen: | Recombinant protein corresponding to Mouse RbAp48 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: | Q60972 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 3000 | lung, kidney, ovary, uterus |
IF | Mouse, Rat | 1: 250-1: 750 | lung, kidney, ovary, uterus |
Background
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse lung using RbAp48 (GB11969) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using RbAp48 (GB11969) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using RbAp48 (GB11969) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat ovary using RbAp48 (GB11969) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat terus using RbAp48 (GB11969) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
