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| Reactivity: | H,M,R & H,M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Rel B rabbit polyclonal antibody |
Gene Name: | Transcription factor RelB |
Synonyms: | Reticuloendotheliosis viral oncogene homolog B, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, IREL, v rel avian reticuloendotheliosis viral oncogene homolog |
Immunogen: | Recombinant protein corresponding to Mouse Rel B |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 60 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q01201, Q04863, Q9EQX9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1:500-1:1000 | kidney, colon |
IHC/IF | Human, Mouse | 1:1000-1:2000 | colon, colon cancer, small intestine |
Background
RelB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.
Images
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Western blot analysis of Relb (GB11985) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human colon cancer using Relb (GB11985) at dilution of 1: 1000 (250x lens) |
 | Immunohistochemistry of paraffin embedded human colon using Relb (GB11985) at dilution of 1: 1000 (250x lens) |
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Immunohistochemistry of paraffin embedded mouse small intestine using Relb (GB11985) at dilution of 1: 1000 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
