Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Retinoic acid receptor gamma |
Synonyms: | NR1B3, RAR gamma, RARC, RARG, Retinoic acid receptor gamma, retinoic acid receptor, gamma |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Retinoic Acid Receptor gamma |
Uniprot ID: | P18911 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 51 kDa / 50 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 2000 | HeLa, Hep G2, MCF7, A-431, HaCaT |
Background
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
Images
Western blot analysis of RARG (GB114773) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |