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Anti-RhoA + RhoC Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RhoA + RhoC rabbit polyclonal antibody |
Gene Name: | Transforming protein RhoA |
Synonyms: | RhoA, ARH12, ARHA, RHO12, RHOH12, ras homolog family member A, ARH9, H9, Rho-related GTP-binding protein RhoC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RhoA . |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 KDa |
Observed MW. | 22 KDa |
Uniprot ID: | P61586, Q9QUI0, P61589 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | lung, kiney |
Background
Ras homolog gene family, member A (RhoA) is a small GTPase protein in the Rho family. RhoA is primarily involved in these activities: actin organization, myosin contractility, cell cycle maintenance, cellular morphological polarization, cellular development and transcriptional control. There are many molecules can stimulate RhoA, such as NgR1, LINGO1, p75, TROY and other unknown receptors (e.g. by CSPGs). The activated RhoA stimulates ROCK (RhoA kinase), which stimulates LIM kinase, which then stimulates cofilin, which effectively reorganizes the actin cytoskeleton of the cell.
Images
| Western blot analysis of RhoA+RhoC (GB11516) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
