Your shopping cart is empty!
Anti-SAM68 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SAM68 rabbit polyclonal antibody |
Gene Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
Synonyms: | GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, Khdrbs1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SAM68 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 48 kDa |
Observed MW. | 68 kDa |
Uniprot ID: | Q07666, Q60749, Q91V33 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, brain |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, breast cancer, lung, lung cancer, ovarian cancer, ovary, skeletal muscle, skin |
Background
SAM68, also named as KHDRBS1, p62and p68, belongs to the KHDRBS family. It is recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, SAM68 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP.
Images
|
|
Western blot analysis of SAM68 (GB111224) at dilution of 1: 500 |
|
|
Immunohistochemistry of paraffin embedded human lung cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human ovarian cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse lung using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse skeletal muscle using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat ovary using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat skeletal muscle using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat skin using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human breast cancer using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse skin using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat brain using SAM68 (GB111224) at dilution of 1: 1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
