Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SENP1 rabbit polyclonal antibody |
Gene Name: | Sentrin-specific protease 1 |
Synonyms: | SUMO-1 protease 2, SuPr-2, Senp1, Supr2, Sentrin/SUMO-specific protease SENP1 |
Immunogen: | Recombinant protein corresponding to Mouse SENP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 73 kDa |
Observed MW. | 75 kDa |
Uniprot ID: | Q9P0U3 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, HepG2, HUVEC, Jurkat, K562 |
Background
SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.
Images
Western blot analysis of SENP1 (GB111438) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |