Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | SH3 domain-binding glutamic acid-rich protein |
Synonyms: | 21 GARP, 21 glutamic acid rich protein, SH3BGR, SH3BGR protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SH3BGR |
Uniprot ID: | Q9WUZ7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 23 kDa / 28 kDa |
Product Usage Information
WB | Mouse | 1: 500-1: 2000 | skeletal muscle |
Background
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.
Images
Western blot analysis of SH3BGR (GB115342) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |