Reactivity: | H,M,R & H,M,R |
Applications: | IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SIN1 rabbit polyclonal |
Gene Name: | Target of rapamycin complex 2 subunit MAPKAP1 |
Synonyms: | Mapkap1, MAPKAP1, JC310, MIP1, SIN1, SIN1b, SIN1g, Mitogen-activated protein kinase associated protein 1 |
Immunogen: | Recombinant protein corresponding to Mouse SIN1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cell membrane |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 1500 | colon, testis, brain |
IF | Human, Mouse, Rat | 1: 400-1: 800 | colon, testis, brain |
Background
Target of rapamycin complex 2 subunit MAPKAP1 is a protein encoded by the MAPKAP1 gene. As the name indicates, it is a subunit of mTOR complex 2. This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.
Images
Immunohistochemistry analysis of paraffin-embedded human colon using SIN1 (GB11837) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded mouse testis using SIN1 (GB11837) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat testis using SIN1 (GB11837) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using SIN1 (GB11837) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using SIN1 (GB11837) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |