Reactivity: | H,M,R & R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SLC22A1/OCT1 rabbit polyclonal |
Gene Name: | Solute carrier family 22 member 1 |
Synonyms: | HOCT1, OCT1, oct1_cds, Organic cation transporter 1, SLC22A1, Lx1, mOCT1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SLC22A1/OCT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 62 kDa |
Observed MW. | 72 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, brain, kidney |
IHC | Rat | 1: 600-1: 1200 | duodenum, kidney |
Background
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
Images
Western blot analysis of SLC22A1 (GB113735) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded rat duodenum using SLC22A1 (GB113735) at dilution of 1: 1200 | |
Immunohistochemistry analysis of paraffin-embedded rat kidney using SLC22A1 (GB113735) at dilution of 1: 1200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |