Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SLC25A6 rabbit polyclonal antibody |
Gene Name: | ADP/ATP translocase 3 |
Synonyms: | ANT 2, Adenine nucleotide translocator 3, ANT3, Solute carrier family 25 member 6, SLC25A6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human SLC25A6 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 30 kDa |
Uniprot ID: | P12236 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | lung, prostate |
Background
SLC25A6 (solute carrier family 25, member A6) participates in the exchange of ADP and ATP across the mitochondrial inner membrane. It may be involved in the formation of the permeability transition pore complex (PTPC), a multiprotein complex built up at the contact site between the inner and the outer mitochondrial membranes. Opening of the PTPC causes massive swelling of mitochondria, rupture of the outer membrane and release of intermembrane components that induce apoptosis.
Images
Western blot analysis of SLC25A6 (GB112438) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |