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Anti-SLC40A1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SLC40A1 rabbit polyclonal antibody |
Gene Name: | Solute carrier family 40 member 1 |
Synonyms: | Ferroportin-1, Iron-regulated transporter 1, Metal transporter protein 1, MTP1, Slc40a1, Fpn1, Ireg1, Slc11a3, Slc39a1 |
Immunogen: | Recombinant protein corresponding to Mouse SLC40A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. | 63 kDa |
Observed MW. | 63 kDa |
Uniprot ID: | Q9NP59, Q9JHI9, Q923U9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | liver, kidney, colon |
IHC | Human, Mouse, Rat | 1:1200-1:2400 | breast cancer, small intestine, gastric cancer, spleen, colon |
Background
SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
Images
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Western blot analysis of SLC40A1 (GB111471) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human breast cancer using SLC40A1 (GB111471) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded human small intestine using SLC40A1 (GB111471) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded human gastric cancer using SLC40A1 (GB111471) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded mouse colon using SLC40A1 (GB111471) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded mouse spleen using SLC40A1 (GB111471) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
