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Anti-SLFNL1 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Schlafen-like protein 1 |
Synonyms: | schlafen like 1, Schlafen like protein 1, SLFNL1 |
Immunogen: | Recombinant protein corresponding to Mouse SLFNL1 |
Uniprot ID: | Q8BHW9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 46 kDa |
Product Usage Information
WB | Mouse | 1: 1000-1: 2000 | testis |
Background
SPTLC1 (serine palmitoyltransferase 1), also known as LCB1, and SPTLC2 (serine palmitoyltransferase 2), also known as LCB2, together catalyze sphingolipid biosynthesis by converting L-serine and palmitoyl-CoA to 3-oxosphinganine, utilizing pyridoxal 5'-phosphate as a cofactor. Increases in transepidermal water loss triggers upregulation of serine palmitoyltransferase mRNA expression in humans. Deficiencies in wild type SPTLC1 and SPTLC2 can lead to hereditary sensory neuropathy, atopic eczema, and psoriasis
Images
| Western blot analysis of SLFNL1 (GB114209) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
