Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SM22 alpha rabbit polyclonal |
Gene Name: | Transgelin |
Synonyms: | TAGLN, SM22, SMCC, TAGLN1, WS3-10, transgelin, SM22-alpha, Transgelin, SM22α |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SM22α |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | stomach, colon |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 3000 | carditis, muscle, skeletal muscle |
Background
Transgelin is a protein that in humans is encoded by the TAGLN gene.
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
Images
Western blot analysis of SM22α (GB11366) at dilution of 1: 600. Lane 1: Mouse stomach tissue lysate Lane 2: Mouse colon tissue lysate Lane 3: Rat stomach tissue lysate Lane 4: Rat colon tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded mouse carditis using SM22α (GB11366) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat carditis using SM22α (GB11366) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse muscle using SM22α (GB11366) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat muscle using SM22α (GB11366) at dilution of 1: 1500 | |
Immunofluorescent analysis of paraffin-embedded mouse bone using SM22α (GB11366) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraffin-embedded mouse heart using SM22α (GB11366) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraffin-embedded mouse skeletal muscle using SM22α (GB11366) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraffin-embedded rat lung using SM22α (GB11366) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |