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Anti-SOX10 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Transcription factor SOX-10 |
Synonyms: | Sox10, DOM, PCWH, WS2E, WS4, WS4C, SRY-box 10 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SOX10 |
Uniprot ID: | Q04888 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 50 kDa / 50-60 kDa |
Product Usage Information
WB | Mouse | 1: 300-1: 600 | brain |
Background
Transcription factor that plays a central role in developing and mature glia Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination Once induced, MYRF cooperates with SOX10 to implement the myelination program Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
Images
| WB analysis of SOX10 (GB115513). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
