Reactivity: | R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ST8SiaIII rabbit polyclonal |
Gene Name: | Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase |
Synonyms: | Sialyltransferase 8C, SIAT8-C, Sialyltransferase St8Sia III, ST8SiaIII, St8sia3, Siat8c |
Immunogen: | Recombinant protein corresponding to Mouse ST8SiaIII |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Golgi apparatus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 2000-1: 4000 | substantia nigra |
Background
Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.
Images
Immunohistochemistry analysis of paraffin-embedded rat substantia nigra using ST8SiaIII (GB112675) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |