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Anti-STAT1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | STAT1 rabbit polyclonal |
Gene Name: | Signal transducer and activator of transcription 1 |
Synonyms: | CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91 |
Immunogen: | Recombinant protein corresponding to Mouse STAT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 87 kDa |
Observed MW. | 87 kDa |
Uniprot ID: | P42224, P42225 |
Applications
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, brain |
IHC | Human | 1: 750-1: 1500 | liver cancer, esophageal cancer |
Background
STAT1 (signal transducers and activators of transcription 1) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.
Images
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Western blot analysis of STAT1 (GB111363) at dilution of 1: 1000 Lane 1: MCF7 cell lysate Lane 2: Hela cell lysate Lane 3: HepG2 cell lysate Lane 4: Mouse testis tissue lysate Lane 5: Mouse brain tissue lysate Lane 6: Rat testis tissue lysate Lane 7: Rat brain tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using STAT1 (GB111363) at dilution of 1: 750 |
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Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using STAT1 (GB111363) at dilution of 1: 750 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
