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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | StAR rabbit polyclonal antibody |
Gene Name: | Steroidogenic acute regulatory protein, mitochondrial |
Synonyms: | StAR, Luteinizing hormone-induced protein, START domain-containing protein 1, StARD1, Star |
Immunogen: | Recombinant protein corresponding to Mouse StAR |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 32 kDa |
Observed MW. | 32 kDa |
Uniprot ID: | P51557, P97826 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | testis |
Background
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH.
Images
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Western blot analysis of stAR (GB111430) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
