Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Superoxide Dismutase 1 rabbit polyclonal antibody |
Gene Name: | Superoxide dismutase |
Synonyms: | Sod1, ALS, ALS1, Amyotrophic lateral sclerosis 1 adult, Epididymis secretory protein Li 44, Cu/Zn SOD, SODC |
Immunogen: | Recombinant protein corresponding to Mouse Superoxide Dismutase 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 16 kDa |
Observed MW. | 18 kDa |
Uniprot ID: | P08228, P07632 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney, liver |
Background
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Images
Western blot analysis of SOD1 (GB112451) at dilution of 1: 500 | |
Western blot analysis of SOD1 (GB112451) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |