Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: |
Superoxide Dismutase 1 rabbit polyclonal |
Gene Name: |
Superoxide dismutase [Cu-Zn] |
Synonyms: |
ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodime |
Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse SOD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: |
Cytoplasm,Mitochondrion,Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:300-1:600 | liver,brain |
IF | Human, Mouse, Rat | 1:300-1:600 | liver,brain |
Background
SOD1 binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying freesuperoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide.Hydrogen peroxide can then be broken down by another enzyme called catalase.
Images
Immunohistochemistry analysis of paraffin-embedded human liver using SOD1 (GB11263) at dilution of 1:300 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using SOD1 (GB11263) at dilution of1:600 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using SOD1 (GB11263) at dilution of 1: 1:300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |