Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TELO2 rabbit polyclonal |
Gene Name: | Telomere length regulation protein TEL2 homolog |
Synonyms: | CLK2, hCLK2, KIAA0683, Protein clk 2 homolog, TEL2, TELO2 |
Immunogen: | Recombinant protein corresponding to Mouse TELO2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 93 kDa |
Observed MW. | 95 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, testis |
Background
TELO2 gene encodes a telomere length regulation protein TEL2 homolog. TELO2 may be involved in telomere length regulation and can form TTT complex with TTI1 and TTI2. TTT complex is required to stabilize protein levels of PIKK family proteins and is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and MMC. The activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals, can be promoted, stabilized and maintained by TELO2.
Images
Western blot analysis of TELO2 (GB112963) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |