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Anti-TGF beta 3 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide; Transforming growth factor beta-3] |
Synonyms: | ARVD, TGF beta 3, TGF beta3, TGFB3, TGF-beta 3, TGF-β3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TGF beta 3 |
Uniprot ID: | P17125 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 47 kDa / 50 kDa |
Product Usage Information
WB | Mouse | 1: 300-1: 600 | heart |
Background
Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. ; [Latency-associated peptide]: Required to maintain the Transforming growth factor beta-3 (TGF-beta-3) chain in a latent state during storage in extracellular matrix . Associates non-covalently with TGF-beta-3 and regulates its activation via interaction with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-3 . Interaction with integrins results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-3 .
Images
| Western blot analysis of TGFb3 (GB114682) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
