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Anti-TGF beta Receptor I Rabbit pAb (100 μl)
| Reactivity: | H,R,M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TGF beta Receptor I rabbit polyclonal antibody |
Gene Name: | TGF-beta receptor type-1 |
Synonyms: | AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TGFR-1, TGFβR1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human TGF beta Receptor I |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P36897 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:600-1:1200 | ovarian cancer, placenta, stomach, kidney, spleen |
Background
Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.
Images
| Immunohistochemistry analysis of paraffin embedded mouse kidney using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat kidney using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunofluorescent analysis of paraffin embedded rat kidney using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human ovarian cancer using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human placenta using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human stomach using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat spleen using TGFβR1 (GB114126) at dilution of 1: 800 |
| Immunofluorescent analysis of paraffin embedded mouse kidney using TGFβR1 (GB114126) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
