Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TLR1 rabbit polyclonal antibody |
Gene Name: | Toll-like receptor 1 |
Synonyms: | Tlr1, TLR1, CD281, TIL, TIL. LPRS5, Rsc786, Toll like receptor 1 |
Immunogen: | Recombinant protein corresponding to Mouse TLR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 500-1: 2000 | lung, spleen |
Background
TLR1 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression.
Images
Immunohistochemistry of paraffin embedded rat lung using TLR1 (GB11886) at dilution of 1:1500 (200x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using TLR1 (GB11886) at dilution of 1:1000 (300x lens) | |
Immunohistochemistry of paraffin embedded rat lung using TLR1 (GB11886) at dilution of 1:1000 (400x lens) | |
Immunofluorescence of paraffin embedded rat lung using TLR1 (GB11886) at dilution of 1:1000 (200x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |