Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TMEM176A rabbit polyclonal antibody |
Gene Name: | Transmembrane protein 176A |
Synonyms: | Gene signature 188, Kidney-expressed gene 2 protein, TMEM176A, Gs188, Keg2, HCA112 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TMEM176A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | Q4G068 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 500-1: 1000 | brain, lung |
Background
TMEM176A is a 235 amino acid multi-pass membrane protein belonging to the TMEM176 family. The gene encoding GS188 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
Images
Immunohistochemistry of paraffin embedded rat brain using TMEM176A (GB111894) at dilution of 1:500 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lung using TMEM176A (GB111894) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |