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Anti-TNF-alpha Mouse mAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Tumor necrosis factor alpha |
Synonyms: | TNF,DIF,TNF-alpha,TNFA,TNFSF2,Tumour necrosis factor, Tumour necrosis factor alpha, TNF-伪, tumor necrosis factor, TNLG1 |
Immunogen: | Recombinant protein corresponding to Mouse TNF-alpha |
Uniprot ID: | P06804 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 30 kDa / 25/28 kDa |
Product Usage Information
WB | Mouse | 1: 500-1: 1000 | RAW 264.7+LPS+Brefeldin A |
Background
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity).
Images
| WB analysis of TNF-alpha (GB12188). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
