Reactivity: | H,M |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TNFAIP8L3 rabbit polyclonal antibody |
Gene Name: | Tumor necrosis factor alpha-induced protein 8-like protein 3 |
Synonyms: | TNF alpha-induced protein 8-like protein 3, TNFAIP8-like protein 3, Tnfaip8l3 |
Immunogen: | Recombinant protein corresponding to Mouse TNFAIP8L3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 23 kDa |
Observed MW. | 23 kDa |
Uniprot ID: | Q5GJ75, Q3TBL6 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, colon |
Background
Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
Images
Western blot analysis of TNFAIP8L3 (GB112660) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |