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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TNNC1 rabbit polyclonal antibody |
Gene Name: | Troponin C, slow skeletal and cardiac muscles |
Synonyms: | Tnnc1, TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC, Troponin C type 1, Troponin C1, Slow skeletal and cardiac type |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TNNC1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 18 kDa |
Observed MW. | 18 kDa |
Uniprot ID: | P19123 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1: 1500 | heart, muscle, kidney |
Background
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Images
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Western blot analysis of Cardiac Troponin C (GB11824) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
