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Anti-TPPP3 Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TPPP3 rabbit polyclonal |
Gene Name: | Tubulin polymerization-promoting protein family member 3 |
Synonyms: | Tppp3, CGI-38, p20, p25gamma, TPPP/p20 |
Immunogen: | Recombinant protein corresponding to Mouse TPPP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton |
Predicted MW. | 19 kDa |
Observed MW. | 19 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | 293, PC3, A549 |
IHC | Human | 1: 1500-1: 3000 | breast cancer, kidney cancer, uterine cancer |
Background
TPPP3 (tubulin polymerization promoting protein 3), also named as TPPP/p20, is a new member of the TPPP family which binds tubulin and induces tubulin polymerization and microtubule bundling.TPPP3 has been shown to play an important role in cell proliferation and may be implicated in tumorigenesis and metastasis . TPPP3 was also identified as specific marker for the connective tissues that envelope tendons due to its distinct expression in the developing tendon sheath . This antibody detects the 19-20 kDa TPPP3 in HeLa and PC-3 cells. The non-specific bands between 40 and 60 kDa were also occasionally observed.
Images
| Western blot analysis of TPPP3 (GB112684) at dilution of 1: 2000 Lane 1: 293 cell lysate Lane 2: PC3 cell lysate Lane 3: A549 cell lysate |
| Immunohistochemistry analysis of paraffin-embedded human breast cancer using TPPP3 (GB112684) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded human kidney cancer using TPPP3 (GB112684) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded human uterine cancer using TPPP3 (GB112684) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
